Hospital site operations manager Matthew Noone said the donation meant the machines – used to deliver anaesthetic gases, and monitor a patient's vital signs during an operation – could be upgraded ahead of schedule.
"This donation, like others we are lucky to receive, allows us to stretch our budget further – meaning patients and staff benefit from improvements to the hospital more quickly," Mr Noone said.
Epping Eastwood Lions Club immediate past president Lynn Campbell said much of the money had been raised at a trivia night held earlier this year.
"The attachment between Ryde Hospital, the local community and our club is very strong," she said.
"It is a real pleasure for us to be able to contribute to the vital work of Ryde Hospital by providing tangible help – this time, in the form of cash to upgrade important equipment.
"I'd like to thank everyone who supports Lions, and supported our trivia night, because they all played a role in making Ryde Hospital an even better asset for our community."