Mr Dominello welcomed the upgrade which provides more floor space, better room configuration and increased levels of comfort for local patients and their visitors.
"I have a special affinity with Ryde Hospital as my sisters and I were all born here," Mr Dominello said.
"I am pleased that the NSW Government has delivered on its commitment, investing $9 million in upgrading and improving the Hospital's facilities."
Minister Hazzard said the new Critical Care Unit is a major development for the treatment of seriously ill or injured patients at Ryde Hospital.
"The new Critical Care Unit means patients requiring coronary and intensive care will be in a first-class facility with the latest equipment," Mr Hazzard said.
"This major upgrade brings Ryde Hospital well and truly into the 21st century.
Patients' relatives can now take advantage of a family lounge in Ward 2 and a quiet room in Critical Care for meetings with staff, or to reflect in privacy.
The unit includes a room specifically designed for palliative care patients at the end of their life to have privacy in a comfortable space with their loved ones.
New air conditioning, equipment, furniture and art works ensure the new wards are as comfortable and pleasant as possible for patients and visitors.
Mr Dominello and Minister Hazzard also met with Mums@Ryde to inspect recent improvements to the birth unit, which include expansion of the birth unit area, co-location of antenatal clinics into the birth unit, re-painting of walls, improved mobile phone coverage and creation of new large waiting/family room.
"It is pleasing to see that having advocated alongside the Mums@Ryde, the upgrade of the birth unit is underway," Mr Dominello said.