Hornsby Ku-ring-gai Hospital is a major metropolitan teaching hospital. Patients can access a range of services including coronary care, intensive care, orthopaedics, general medicine, surgical, obstetric, respiratory, rehabilitation, paediatric, maternity and emergency care. The hospital also provides a wide range of outpatient services including allied health, dental and podiatry clinics, child, adolescent and family health, drug and alcohol, health promotion and rehabilitation and aged care. An acute mental health service is co-located at Hornsby Hospital.
The hospital underwent a $265 million redevelopment, which was completed in 2021. The redevelopment includes a refurbished and expanded emergency department and a new clinical services building.